In my experience with hiring, a real simple one is to ask (while holding their resume), “Can you tell me about yourself?” Sure, I can read what it says, but letting them verbalize usually is a good indicator. In one of the last sets of interviews I did I asked a candidate this question and I got a gruff response, “It is all right there, what do you need to know?” Good communication skills? No, see you later.
One other question I like is, “What are two character flaws you have?” Usually someone prepares for one in advance with something like, “I am an over-committed worker…” or other statement that is meant to actually show a positive side about them. Asking for two lets you watch for quick thinking and (again) communication skills. In our industry technical is a must, but people can be trained. If you are bad at communicating or just a jerk, then no amount of training can help.
Anyone else have some good interview Q’s?